Knowledge of Hepatitis B Virus and Vaccination Uptake among Pregnant Women in Rural North Gonja of the Savanah Region, Ghana
Asian Journal of Pregnancy and Childbirth,
Purpose: Hepatitis B viral(HBV) infection is a global public health challenge. Mother to child transmission is the leading cause of HB Vinfection in high endemic countries. The objective of this study was to examine pregnant women’s knowledge of HBV and their vaccination uptake in the North Gonja District of the Savanah Region of Ghana.
Methods: A facility-based cross-sectional study was conducted in five Health centres and five Community-based Health Planning and Services(CHPS) compounds.Data was collected from April to June 2020 using a structured questionnaire. Data on socio-demographic characteristics,HBV Knowledge, testing and vaccination uptake among 310 pregnant women attending ante-natal clinics (ANC) were collected using a simple random sampling method. The data was analyzed using Microsoft Excel version 2019 and IBM SPSS v25. Results were presented as frequencies, percentages, tables and figure. A chi-square test of associations was performed and a P-value of <0.05 was considered statistically significant.
Results: In all, 43.25% of the respondents had excellent knowledge, 21.94% had good knowledge whilst 34.84% had poor knowledge. There was a statistical association between educational level (p=0.002), ANC visit (p<0.001), ethnicity (p<0.001), occupation(p<0.011) and knowledge of HBV. HBV testing and vaccination uptake were only 35.5% and close to 33% respectively. Educational level (p<0.001), previous HBV screening (p<0.001), occupation (p<0.001), knowledge of HBV(p<0.001), ANC visit(p=0.002) were significantly associated with Hepatitis B virus vaccination uptake.
Conclusion: Pregnant women were knowledgeable of HBV. However, HBV testing and vaccination uptake were low. Pregnant women attending ANC should be screened for hepatitis B. Vaccination of pregnant women against HBV should be introduced into the EPI program.
- Hepatitis B
- vaccination uptake
- pregnant women
- North Gonja
How to Cite
WHO. Global Hepatitis Report; 2017.
Dun-Dery F, Adokiya MN, Walana W, Yirkyio E, Ziem JB. Assessing the knowledge of expectant mothers on mother-to-child transmission of viral hepatitis B in Upper West region of Ghana,” BMC Infect. Dis. 2017;17(1): 1–10.
Awiah EA. Prevalence and Predictors of Hepatitis B among Pregnant Women Attending Antenatal Care in Wa Municipality. University of Ghana; 2018.
Gentile I, Borgia G. Vertical transmission of hepatitis B virus: challenges and solutions. Int. J. Womens. Health. 2014;6:605.
Abdulai MA, Baiden F, Adjei, G, Owusu-Agyei S. Low level of Hepatitis B knowledge and awareness among pregnant women in the Kintampo North Municipality: implications for effective disease control. Ghana Med. J. 50(3):157–162.
WHO. Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection. Guidel. Prev. care Treat. Pers. with chronic Hepat. b Infect. 2015;166.
Ofori-Asenso R, Agyeman AA. Hepatitis B in Ghana: A systematic review & meta-analysis of prevalence studies (1995-2015),” BMC Infect. Dis. 2016; 16(1).
Hang Pham TT, et al. Knowledge, attitudes and practices of hepatitis B prevention and immunization of pregnant women and mothers in northern Vietnam. Plos One. 2019;14(4):e0208154.
Id AA, Fusheini Id A. Knowledge, risk of infection, and vaccination status of hepatitis B virus among rural high school students in Nanumba North and South Districts of Ghana; 2020.
Frambo, AAB, Atashili J, Fon PN, Ndumbe PM. Prevalence of HBsAg and knowledge about hepatitis B in pregnancy in the Buea Health District, Cameroon: A cross-sectional study. BMC Res. Notes. 2014;7(1):394.
Atilola G, et al. Epidemiology of HBV in pregnant women, South West Nigeria. J. Epidemiol. Glob. Health. 2018;8(3–4):115.
Abdulai MA, Baiden F, Adjei G, Owusu-Agyei S.Low level of Hepatitis B knowledge and awareness among pregnant women in the Kintampo North Municipality: implications for effective disease control.,” Ghana Med. J., vol. 50, no. 3, pp. 157–162, 2016, [Online]. Available: http://www.ncbi.nlm.nih.gov/pubmed/27752190%0Ahttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC5044795.
Zimtani R. University of Ghana; 2018.
http://ugspace.ug.edu.gh,” no. 10635127,
Adeyemi AB, Enabor OO, Ugwu IA, Bello FA, Olayemi OO. Knowledge of hepatitis B virus infection, access to screening and vaccination among pregnant women in Ibadan, Nigeria. J. Obstet. Gynaecol. (Lahore). 2013;33(2):155–159.
Eni AO, Soluade MG, Oshamika OO, Efekemo OP, Igwe TT, Onile-Ere OA. Knowledge and awareness of hepatitis B virus infection in Nigeria,” Ann. Glob. Heal. 2019;85(1):1–6.
GSS. North Gonja District; 2014.
Kwadzokpui PK, Akorsu EE, Abaka-Yawson A, Quarshie SS, Amankwah SA, Tawiah PA. Prevalence and Knowledge of Hepatitis B Virus Infection among Pregnant Women in the Ningo-Prampram District, Ghana. Int. J. Hepatol; 2020.
Yankam BM, Anye CS, Nkfusai NC, Shirinde J, Cumber SN. Knowledge and practice of pregnant women and health care workers on hepatitis B prevention in the Limbe and Muyuka health districts of the south west region of Cameroon. Pan Afr. Med. J. 2019;33.
Eyong EM, et al. The prevalence of HBsAg, knowledge and practice of hepatitis B prevention among pregnant women in the Limbe and Muyuka Health Districts of the South West region of Cameroon: a three-year retrospective study. Pan Afr. Med. J. 2019;32.
Chan OK, Lao TT, Suen SSH, Leung TY. Deficient Knowledge on Hepatitis B Infection in Pregnant Women and Prevalence of Hepatitis B Surface Antigen Carriage in an Endemic Area: A Review,” Hepat. Res. Treat. 2012:1–8.
Ahmad A, Munn Sann L, Abdul Rahman H. Factors associated with knowledge, attitude and practice related to hepatitis B and C among international students of Universiti Putra Malaysia,” BMC Public Health. 2016;16(1):1–8,
Kolawole OM, Wahab AA, Adekanle DA, Sibanda T, Okoh AI. Seroprevalence of hepatitis B surface antigenemia and its effects on hematological parameters in pregnant women in Osogbo, Nigeria Virol. J. 2012;9( 1):1–6.
Noreen N, Kumar R, Shaikh BT, Knowledge about hepatitis B vaccination among women of childbearing age: a cross-sectional study from a rural district of Punjab, Pakistan,” East Mediterr Heal. J, 2015;21(2):129–133.
Odelola OI, Akadri AA, Shorunmu TO, Hepatitis B virus infection: Knowledge of antenatal attendees in a tertiary hospital,” Niger. J. Med. 2020;29(1):24–28, 2020.
Darwish MA, Al Khaldi NM. Knowledge about hepatitis B virus infection among medical students in university of dammam, eastern region of Saudi Arabia,” Life Sci J. 2013;10(2):860–867.
Rajamoorthy Y, et al. Knowledge and awareness of hepatitis B among households in Malaysia: A community-based cross-sectional survey. BMC Public Health. 2019;19(1):1–11.
Kwadzokpui PK, Akorsu EE, Abaka-Yawson A, Quarshie SS, Amankwah SA, Tawiah PA. Prevalence and knowledge of hepatitis B virus infection among pregnant women in the Ningo-Prampram district, Ghana. Int. J. Hepatol; 2020.
Rabiu KA, Akinola OI, Adewunmi AA, Omololu OM, Ojo TO. Risk factors for hepatitis B virus infection among pregnant women in Lagos, Nigeria,” Acta Obstet. Gynecol. Scand. 2010;89(8):1024–1028.
Gebrecherkos T, Girmay G, Lemma M, Negash M. Knowledge, Attitude, and Practice towards Hepatitis B Virus among Pregnant Women Attending Antenatal Care at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. Int. J. Hepatol; 2020,
Gostin LO, Burris S, Lazzarini Z. The law and the public’s health: a study of infectious disease law in the United States,” Colum. L. Rev. 1999;99:59.
Schillie S, et al. Prevention of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices,” MMWR Recomm. Reports. 2018;67(1): 1.
Nankya-Mutyoba J, Aizire J, Makumbi F, Atuyambe L, Kirk G, Ocama P. Hepatitis B Prevalence among Pregnant Women in Central and West Nile regions of Uganda: Is there a Need to prioritize Prevention of Mother to Child hepatitis B transmission?; 2019.
Kolasa MS, Tsai Y, Xu J, Fenlon N, Schillie S. Hepatitis B surface antigen testing among pregnant women, United States 2014. Pediatr. Infect. Dis. J. 2017; 36(7):e175–e180.
Mengouo AM, Halle-Ekane GE, Mengouo MN, Njamen TN, Nwain HM, Namme HL, Hepatitis B in Pregnancy: Knowledge, Access to Screening and Vaccination in a Low-Resource Setting, Cameroon. Asian J. Res. Med. Pharm. Sci. 2018;1–10.
Umare A, Seyoum B, Gobena T, Haile Mariyam T. Hepatitis B virus infections and associated factors among pregnant women attending antenatal care clinic at Deder Hospital, Eastern Ethiopia. Plos One. 2016;11(11):e0166936.
Bayo P, Ochola E, Oleo C, Mwaka AD. High prevalence of hepatitis B virus infection among pregnant women attending antenatal care: A cross-sectional study in two hospitals in northern Uganda,” BMJ Open. 2014;4(11):1–7.
Schillie SF, et al. CDC guidance for evaluating health-care personnel for hepatitis B virus protection and for administering postexposure management; 2013.
Ministry of Health G. National Community Health Planning and Services (CHPS) Policy; 2014.
Ghana Health Service. Ghs Standard Hospitals. 2016;1–25.
Abstract View: 167 times
PDF Download: 24 times