Prevalence of Falciparum Malaria in Relation to Age, Gravidity, Trimester, Blood Group and Genotype among Pregnant Women

Main Article Content

J. C. Ozougwu
C. A. Imakwu
J. E. Ekeleme
O. P. Okeke
G. U. Amana
S. C. Eziuzor
J. C. Ogbodo

Abstract

Aim: This study was undertaken to ascertain the prevalence of falciparum malaria in relation to age, gravidity, trimester, blood group and genotype among pregnant women attending antenatal in Model Primary Health Centre, Omoku, Rivers State.

Methodology: The study was carried out from January to December, 2019, venous blood samples were collected from six hundred and ten pregnant women selected by simple random sampling, thick and thin blood films were made, stained with giemsa stain and viewed under the light microscope. ABO Blood group and haemoglobin genotype were determined using standard methods. Statistical result was performed using statistical package for social sciences version 20.

Results: The overall prevalence of malaria in relation to age showed that out of the 610 pregnant women tested, 320 were positive for malaria giving an overall prevalence of 52.5℅. The age group between 46 – 50 yrs had the highest prevalence of malaria 100%, while the age group 36-40 yrs recorded the least prevalence of malaria 11.1℅. The prevalence of malaria in relation to gravidity showed that the multigravida had higher prevalence (96.3%) than primigravida which had 45.5℅. The overall prevalence of malaria in relation to gravidity is 54.9%.  With regards to trimester, it showed that pregnant women in their second and third trimester both had the highest prevalence of malaria 57.0℅, while those in the first trimester had the lowest prevalence of 50℅. For blood group it showed that the blood group with the highest prevalence was AB (76.1%), while blood group A had the least prevalence (24.7℅). The overall prevalence of malaria in relation to blood group is 55.6%. In relation to genotype, it showed that genotype AA had the highest prevalence of 85.2℅, while the least prevalence was seen among AS genotype (35.4℅). Prevalence values were statistically significant at P < 0.05. 

Conclusion: This study showed that malaria in pregnancy is still endemic in Omoko, Rivers State, Nigeria. The high prevalence observed in most groups could be because rainy season lasts longer yearly which favours the breeding of Anopheles Mosquito, the malaria vector. There is need for adequate enlightenment on the malaria preventive and control measures to reduce the prevalence of malaria in pregnancy.

Keywords:
Prevalence, Plasmodium falciparum, age, gravidity, trimester, blood group, genotype, pregnant women.

Article Details

How to Cite
Ozougwu, J. C., Imakwu, C. A., Ekeleme, J. E., Okeke, O. P., Amana, G. U., Eziuzor, S. C., & Ogbodo, J. C. (2020). Prevalence of Falciparum Malaria in Relation to Age, Gravidity, Trimester, Blood Group and Genotype among Pregnant Women. Asian Journal of Pregnancy and Childbirth, 3(4), 1-7. Retrieved from https://journalajpcb.com/index.php/AJPCB/article/view/30123
Section
Original Research Article

References

World Health Organization: World Malaria Report (2019). World Health Organization, Geneva; 2019.

WHO. Global technical strategy for malaria (2016-2030). World Health Organization. 20 Avenue Appia, 1211 Geneva 27; 2015. Switzerland.

World Health Organization: World Malaria Report (2018). World Health Organization, Geneva; 2018.

Adefioye OA, Adeyeba, OA Hassan WO, Oyeniran OA. Prevalence of Malaria Infection among pregnant women in Osogbo South West Nigeria. American- Eurasian Journal of Scientific Research. 2007;2(1):43-5.

Odongo CO, Odida M, Wabinga H, Obua C, Byamugislic J. Burden of placental malaria among pregnant women who use or do not use intermittent preventive treatment at Mulago Hospital, Kampala. Malaria Research and Treatment. 2016; 8-14.

Emiasegen SM, Fatima JG, Ajumobi O, Ajayi IO, Ahmed SA, Olayinka AT. (2017). Asymptomatic Plasmodium falciparum parasitaemia among pregnant women: a health facility based survey in Nassarawa-Eggon, Nigeria. Malaria World Journal. 2017;8(7):205-367

Federal Ministry of Health. Malaria situation analysis document. Federal Ministry of Health. 2000;14.

Akanbi OM, Odaibo AB, Olaturegun RS, Ademowo OG. Role of malaria induced stress on anaemia in pregnancy. Asian Pacific Journal of Tropical Medicine. 2010;3:211-4.

Bawa JA, Auta T, Liadi S. Prevalence of Malaria: Knowledge, Attitude and Cultural practices of Pregnant Women in Katsina Metropolis, Nigeria. European Scientific Journal. 2014;10(21):148-167.

Aribodor DN, Ugwuanyi IK, Aribodor OB. Challenges to Achieving Malaria Elimination in Nigeria. American Journal of Public Health Research, 2016;4(1):38-41.

World Health Organization: World Malaria Report (2014). World Health Organization, Geneva; 2014.

Agbolanho JJ. Response to malaria epidemics in Africa. Emerging Infectious Diseases. 1993;13(5):68–186.

Cheesbrough M. District Laboratory Practice Manual in Tropical Countries, Part 2. Cambridge University Press, Second Edition, New York. 2000;321-340.

WHO. Malaria Diagnosis, New Perspectives. Geneva, World Health Organisation. WHO/CDS/RBM/ 2000.14.

Dacie JV, Lewis SM. Investigation of haematological disorders: Practical haematology. Churchill Livingstone Edinburgh United Kingdom. 2006;177-180.

Iwueze MO, Okwusogu MI, Onyido AE, Okafor FC, Nwaorgu OC, Ukibe AE. Prevalence, Intensity and Clinical profile of malaria among pregnant women attending antenatal clinics in Onitsha North Local Government Area, Anambra State, Southern Nigeria. The Bioscientis. 2014; 2(1):17-9.

Amodu, OK, Olaniyan SA, Adeyemo AA, Trove-Blomberg M, Olumese PE, Omotade OO. Association of Sickle cell trait and the ABO group with clinical severity of malaria in Southwest, Nigeria. Act. Trop. 2012; 123(2):72-77.

Amala SE, Nwibani CP. Malaria in Children, Its Association with ABO blood group and Haemoglobin Genotype. International Journal of Development Research. 2015; 5(11):5958-62.

Uneke CJ, Ogbu O, Nmojiji V. Potential risk of induced malaria by blood transfusion in South East, Nigeria. Mc Gill Journal. Med. 2006;9:8-13.

Olasunkanmi OI, Akhigbe OA, Akinjimi AA, Okerentugba PO, Onajobi IB, Okonko IO. Prevalence of Malaria Plasmodium among children in Abeokuta, Nigeria. Academia Arena. 2013;5(10):41-7.

Okonko IO, Adejuwon AO, Okerentungba PO, Frank PN. Plasmodium falciparum and HIV amomg children presentation at the out patients clinic in Oni Memorial Children hospital in Ibadan Southwestern Nigeria. Nature and Science. 2012;10(8): 94-100.

Gayathri BN, Harendra KML, Gomathi N, Jeevan S, Reethesh RP. Relationship between ABO blood groups and malaria with clinical outcome in rural area of South India. Glob J Med Public Health. 2013;2: 1-7.

Singh G, Urhekar AD, Si R. A study on correlation of malaria infection with A, B, O, RH blood group system. J. Parasitol Vector Biol. 2015;7:67-73.

Esan AJ, Ifeanyichukwu MO. Effect of haemoglobin genotype variants on pre, post anti-malaria drug treatment in Plasmodium falciparum malaria infected and non-infected individuals on blood cell line parameters in Ido- Ekiti. International Journal of Science and Research. 2012;1763–1769.