Consumption of Coconut (Cocos nucifera L.) Water Improved Fertility Parameters in Male Wistar Rats
Asian Journal of Pregnancy and Childbirth,
Background: The need for fertility stimulation in men and women cannot be overemphasized especially when a marriage is childless in some communities in Nigeria. While chemical methods for fertility stimulation may have some side effects and are not readily available, remedy from natural sources can be used.
Aim: This present study is aimed to evaluate the effect of coconut water on fertility in male Wistar rats.
Materials and Methods: Coconuts of about 8 months old were harvested from Apata area of Ibadan in Oyo State, Nigeria. The coconuts were dehusked, broken carefully and the liquid endosperm was collected and preserved in the refrigerator. Thirty male Wistar rats weighing between 180 and 200 g were used for the experiment. They were acclimatized for 7 days during which they were fed ad libitum with standard feed and drinking water. They were randomly divided into 6 groups of 5 rats each. Animals in groups A, B and C were administered normal saline for 10, 20 and 30 days respectively via oral route. Those in groups D, E and F were similarly treated (for 10, 20 and 30 days respectively via oral route) but with 3 mL of undiluted coconut water. At the end of treatment, the animals were sacrificed by the cervical dislocation. The internal organs were exposed. Testes and cauda epididymis were removed and kept in sterilized watched glass. Male fertility parameters were determined using standard methods.
Results: Coconut water caused increased sperm count and sperm motility while mortality and abnormality of spermatozoa decreased significantly after 10, 20 and 30 days of treatment respectively. However, coconut water had no significant difference on seminal pH at P<0.05.
Conclusion: The results of this present study showed that coconut water increased fertility in male Wistar rats. Men with fertility challenges are encouraged to consume coconut water as often as possible.
- Coconut water
- sperm count
- sperm motility
- sperm mortality
- sperm abnormality
- seminal pH.
How to Cite
Esquenazi D, Wigg MD, Miranda MMFS, Rodrigues HM, Tostes JB, Rozental S, Silva AJR, AlvianoCS. Antimicrobial and antiviral activities of polyphenolics from Cocos nucifera Linn (Palmae) huskfiber extract. Res Microbiol. 2002;153:647-652.
Kirszberg C, Esquenazi D, Alviano CS, Rumjanek VM. The effect of a catechin-rich extract of Cocos nucifera on lymphocytes proliferation. Phytother Res. 2003;17:1054-1058.
Alviano DS, Rodrigues KF, Leitão SG, Rodrigues ML, Matheus ME, Fernandes PD, Antoniolli AR, Alviano CS. Antinociceptive and free radical scavenging activities of Cocos nucifera L. (Palmae) husk fiber aqueous extract. J Ethnopharmacol. 2004;92:269-273.
Pummer S, Heil P, Maleck W, Petroianu G. Inﬂuence of coconut water on homeostasis. Am J Emerg Med. 2001;19: 287.
Campbell-Falck D, Thomas T, Falck TM, Tutuo N, Clem K. The intravenous use of coconut water. Am J Emerg Med. 2000;18: 108-111.
Anurag P, Rajamohan T. Cardioprotective effect of tender coconut water in experimental myocardial infarction. Plant Food Hum Nutr. 2003;58:1-12.
Scalbert A, Johnson IT, Saltmarsh M. Polyphenols: Antioxidants and beyond. Am J ClinNutr. 2005;81:215-217.
Mantena SK, Badduri SR, Siripurapu KB, Unnikrishnan MK. In vitro evaluation of antioxidant properties of Cocos nucifera Linn. water. Nahrung. 2003;47:126-131.
Seneviratne KN, Dissanayake DMS. Variation of phenolic content in coconut oil extracted by two conventional methods. Int J Food Sci Tech. 2008;43:597-602.
Chakraborty M, Mitra A. The antioxidant and antimicrobial properties of the methanolic extract from Cocos nucifera mesocarp. Food Chem. 2008;107:994- 999.
Larsen U. Trends in infertility in Cameroon and Nigeria. Int Fam Plan Perspect. 1995; 21(4):138–142.
Akinloye O, Truter EJ. A review of management of infertility in Nigeria: Framing the ethics of a national health policy. International Journal of Women’s Health. 2011;3:265–275.
Van-Zandvoort H, de Koenig K, Gerrits T. Viewpoint: Medical infertility care in low income countries: the case for concern in policy and practice. Trop Med Int Health. 2001;6(7):563–569.
Guide for the Care and Use of Laboratory Animals, 8th edition. Institute for Laboratory Animal Research; 2011.
Nnodim J, Elendu HN, Ihim A, Dimeke C, Ezekwesiri CO. Coconut Water Consumption and Its Effect on Sex Hormone Concentrations. Journal of Krishna Institute of Medical Sciences University. 2014;3(2):107-110.
Eliasson R. Analysis of Semen. In progress in infertility. Eds. S.J. Behrman and R.W. Kistner, Little Brown and company Boston, Vol-II in edition. 1975; Chapter-33,693.
Tijee DY, Ontoeng S. The viscosity of Human Semen and the percentage of motile spermatozoa, Fertile Steril. 1968; 19:562-565.
Edeoga, HO, Okwu DE, Mbaoble BO. Phytochemical constituents of some Nigerian Medicinal Plants. African J Biotechnol. 2005;4(7):685-688.
Airaodion AI, Ogbuagu EO, Ekenjoku JA, Okoroukwu VN, Ogbuagu U, Airaodion EO. Antifertility effect of ethanolic leaf extract of Carica papaya in Male Wistar Rats. Merit Research Journal of Medicine and Medical Science. 2019;7(10):374-381.
Ekenjoku JA, Airaodion AI, Okoroukwu VN, Ogbuagu EO, Ogbuagu U. Oral administration of ethanolic extract of Vernonia amygdalina leaves might impact negatively on fertility in male wistar rats. Asian Journal of Medical Principles and Clinical Practice. 2019;2(3):1-8.
Santos JLA, Bispo VS, Filho ABC, Pinto IFD, Dantas LS, Vasconcelos DF, Abreu FF, Melo DA, Matos IA, Freitas FP, Gomes OF, Medeiros MHG, Matos HR. Evaluation of Chemical Constituents and Antioxidant Activity of Coconut Water (Cocusnucifera L.) and Caffeic Acid in Cell Culture. Annals of the Brazilian Academy of Sciences. 2013;85(4):1235-1246.
Hasim BS, Goverdhan NA, Vengaiah V, Changamma C. Impact of Vernonia amygdalina Linn. Seed extraction on some Marker Enzymes in Male Albino Rats, Int. J. Pharm. Sci. 2013;22 (2):214-217.
Lohiya NK, Kothari LK, Manivannan B, Mishra PK, Pathak N. Human sperm immobilization effect of Vernonia Amygdalina Seeds extract: In vitro study, Asian Journal of Andrological. 2000;2(2): 103-110.
Lohiya NK, Manivannan B, Mishra PK, Pathak N, Sriram S, Bhande SS, Panneerdoss S. Chloroform extract of Vernonia Amygdalina Seeds induced long-term reversible azospermia in lengur monkey. Asian Journal of Andrology. 2002; 4(1):17-26.
Pathak N, Mishra PK, Manivannan B, Lohiya NK. Sterility due to inhibition of sperm motility by oral administration of benzene chromatographic fraction of the chloroform extract of the seed of Vernonia amygdalin ain rats. Phytomedicine. 2000;7: 325-333.
Manivannan B, Mittal R, Goyal S, Ansari AS, Lohiya NK. Sperm characteristics and ultrastructure of testes of rats after long-term treatment with the methanol subfraction of Vernonia amygdalina seeds. Asian J Androl. 2009;11:583–599.
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